1-(2-氯苯基)-1-(4-氯苯基)-2,2-二氯乙烷

产品名称：

53-19-0
Mitotane
1-Chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]-benzene
1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane
2,4′-DDD
o,p′-DDD
米托坦
1-(2-氯苯基)-1-(4-氯苯基)-2,2-二氯乙烷

产品介绍：

产品说明

包装

100 mg in glass bottle

生化/生理作用

Mitotane is a selective inhibitor of sterol-Oacyl-transferase 1 (SOAT1), also known as ACAT1, (acyl-coenzyme A cholesterol acyltransferase). Mitotane inhibition of SOAT1 in adrenocortical carcinoma cells decreased the formation of cholesteryl esters, which increased free cholesterol levels and caused endoplasmic reticulum (ER) stress, the unfolded protein response, and eventually apoptosis.

基本信息

经验(实验)分子式	C₁₄H₁₀Cl₄
分子量	320.04
EC 号	200-166-6
MDL编号	MFCD00000850
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 20 mg/mL, clear
储存温度	2-8℃
SMILES string	ClC1=C(C(C(Cl)Cl)C2=CC=C(Cl)C=C2)C=CC=C1
InChI	1S/C14H10Cl4/c15-10-7-5-9(6-8-10)13(14(17)18)11-3-1-2-4-12(11)16/h1-8,13-14H
InChI key	JWBOIMRXGHLCPP-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H351
预防措施声明	P280
危险分类	Carc. 2
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable