产品说明
一般描述
The gene CACNB1 (calcium voltage-gated channel auxiliary subunit β 1) encodes a member of the calcium channel β subunit family. The gene spanning a length of 25kb contains 13 exons and is mapped to human chromosome 17. Alternative splicing at exons 7 and 13 produces β1a,β1b and βlc isoforms.
特异性
Detects ~80, 55 kDa. No cross-reactivity against Cav Beta4
免疫原
Synthetic peptide amino acids 19-34 of rat CavB1, Accession Number NP_059042
生化/生理作用
The gene CACNB1 (calcium voltage-gated channel auxiliary subunit β 1) encodes the human brain β1 subunit of voltage dependent calcium channels called dihydropyridine receptors (DHPR). They detect changes in membrane voltage by activating ryanodine receptors to release Ca2+ from the sarcoplasmic reticulum into the cytosol, leading to excitation–contraction (EC) coupling.
特点和优势
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外形
Solution in PBS, pH 7.4, 50% glycerol, and 0.09% sodium azide
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | S7-18, monoclonal |
| 形式 | buffered aqueous glycerol solution |
| 分子量 | antigen predicted mol wt 55 kDa antigen predicted mol wt 80 kDa |
| species reactivity | human, rat, mouse |
| 浓度 | 1 mg/mL |
| technique(s) | immunohistochemistry: suitable immunoprecipitation (IP): suitable western blot: suitable |
| 同位素/亚型 | IgG1 |
| NCBI登记号 | NP_059042 |
| UniProt登记号 | Q02641 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | rat ... Cacnb1(50688) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
