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MYO3ALPHA, Active

品牌
Sigma-Aldrich
货号
SRP0728
规格纯度
PRECISIO® Kinase, recombinant
参考价格
5177.2 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
MYO3ALPHA, Active
产品介绍:

产品说明

应用

Useful for kinase assay and Western blot.

生化/生理作用

Recombinant human MYO3alpha (1-434) was expressed by Baculovirus in Sf9 insect cells using an N-terminal GST tag. MYO3alpha belongs to the myosin superfamily which are members of the large myosin superfamily and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as MYO3alpha, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors (1). MYO3alpha plays an important role in hearing in humans and mutations in the MYO3alpha have been shown to cause nonsyndromic progressive hearing loss (2). MYO3alpha is highly expreesed in retina and cochlea.

重悬

Formulated in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, with 25% glycerol.

储存及稳定性

Store in aliquots at -70℃. Avoid freeze/thaw cycles.

法律信息

PRECISIO is a registered trademark of sigma-aldrich Co. LLC

产品性质

重组expressed in baculovirus infected Sf9 cells
测定70-95% (SDS-PAGE)
形式frozen liquid
specific activity3.0-5.0 nmol/min·mg (radiometric)
分子量 ~76 kDa
浓度0.1 μg/μL
登记号NM_017433
运输dry ice
储存温度−70℃
Gene Informationhuman ... MYO3A(53904)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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