产品说明
一般描述
Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signaling is also involved in cellular processes through-out adulthood. Signaling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins.
外形
Lyophilized with PBS.
重悬
Reconstitute with sterile water to 1 mg/mL.
基本信息
| NACRES | NA.32 |
产品性质
| 生物来源 | mouse |
| 重组 | expressed in E. coli |
| 测定 | ≥95% (SDS-PAGE) |
| 形式 | lyophilized |
| 分子量 | calculated mol wt ~87 kDa (The extracellular domain of mouse Notch-2 (aa 26-494) (12 epidermal growth factor-like (EGF) repeats)) |
| 包装 | pkg of 25 μg |
| 杂质 | <0.01 EU/μg endotoxin (LAL test) |
| UniProt登记号 | O35516 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | mouse ... NOTCH2(18129) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
