产品说明
一般描述
Pigment epithelium-derived factor (PEDF) is a 47 kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and fetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells.
外形
Lyophilized in PBS.
重悬
Reconstitute with 100 μsterile distilled water.
基本信息
| NACRES | NA.32 |
产品性质
| 生物来源 | mouse |
| 重组 | expressed in E. coli |
| 测定 | ≥95% (SDS-PAGE) |
| 形式 | lyophilized |
| 分子量 | ~470 kDa (Mouse PEDF aa 20-417 is fused at the C-terminus to a FLAG |
| 包装 | pkg of 10 μg |
| 杂质 | <0.1 EU/μg endotoxin (LAL test) |
| UniProt登记号 | P97298 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | mouse ... Serpinf1(20317) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
