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Procarbazine Hydrochloride

品牌
Sigma-Aldrich
CAS
366-70-1
货号
SML0036
规格纯度
≥98% (HPLC)
参考价格
957.62 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
366-70-1
Procarbazine Hydrochloride
N-(1-Methylethyl)-4-[(2-methylhydrazinyl)methyl]benzamide hydrochloride
产品介绍:

产品说明

应用

Procarbazine, an antineoplastic alkylating agent, may be used to study its pharmacokinetics, metabolism, safety, efficacy and methods of delivery as an anticancer agent. It may be used to study new combination of anticancer drugs.
Procarbazine hydrochloride has been used to study its physicochemical property.

包装

10, 50 mg in glass bottle

生化/生理作用

Procarbazine is an antineoplastic alkylating agent widely used in cancer chemotherapy in combination with other compounds. It has multiple mechanisms of action. Procarbazine inhibits protein, RNA and DNA synthesis in addition to being an alkylating agent.
Procarbazine is metabolized to azoprocarbazine either by cytochrome P450 enzyme and monoamine oxidase in an NADPH (nicotinamide adenine diphosphate) dependent or independent manner. It is considered neurotoxic. Procarbazine is used in combination with therapy for treating Hodgkin′s disease.

基本信息

经验(实验)分子式C12H19N3O·HCl
分子量257.76
EC 号206-678-6
MDL编号MFCD00072082
PubChem化学物质编号329825106
NACRESNA.77

产品性质

测定≥98% (HPLC)
形式powder
颜色 white to tan
溶解性DMSO: ≥18 mg/mL
储存温度2-8℃
SMILES stringCl.CNNCc1ccc(cc1)C(=O)NC(C)C
InChI1S/C12H19N3O.ClH/c1-9(2)15-12(16)11-6-4-10(5-7-11)8-14-13-3;/h4-7,9,13-14H,8H2,1-3H3,(H,15,16);1H
InChI keyDERJYEZSLHIUKF-UHFFFAOYSA-N

安全信息

象形图GHS07GHS08
警示用语:Danger
危险声明H302 - H341 - H350 - H360
预防措施声明P201 - P301 + P312 + P330 - P308 + P313
危险分类Acute Tox. 4 Oral - Carc. 1B - Muta. 2 - Repr. 1A
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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