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Procathepsin K from mouse

品牌
Sigma-Aldrich
货号
SRP6180
规格纯度
recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
参考价格
4764.93 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Procathepsin K from mouse
Cathepsin O
CTSO
CTSO2
Cathepsin O2
CTSK
Cathepsin X
产品介绍:

产品说明

一般描述

Cathepsin K is a member of the papain cysteine proteinase family and has been identified as the predominant proteinase responsible for the resorption of the bone matrix. The enzyme cleaves proteins such as collagen type I, collagen type II and osteonectin and therefore plays a role in bone remodeling and resorption in diseases such as osteoporosis, osteolytic bone metastasis and rheumatoid arthritis (Bromme and Okamoto, 1995; Drake, F. et al 1996; Bossard et al, 1996). Cathepsin K is synthesized as an inactive proenzyme (35.1 kDa) that is converted to its mature active form (23.6 kDa) by proteolytic cleavage of its 99-amino-acid propeptide domain. The in-vitro processing of procathepsin K to mature cathepsin K is autocatalytic.

外形

2.5 mg/mL solution in 25 mM Na2HPO4 and 500 mM NaCl (pH 7.0).

基本信息

NACRESNA.32

产品性质

生物来源mouse
重组expressed in E. coli
测定≥95% (SDS-PAGE)
形式liquid
分子量 35.5 kDa
包装pkg of 1 mg
pkg of 10 μg
pkg of 50 μg
浓度2.5 mg/mL
UniProt登记号P43235
运输dry ice
储存温度−70℃
Gene Informationmouse ... CATK(1513)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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