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SLK, active, GST tagged human

品牌
Sigma-Aldrich
货号
SRP5086
规格纯度
PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
参考价格
6581.15 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
SLK, active, GST tagged human
KIAA0204
bA16H23.1
STK2
se20-9
LOSK
MGC133067
产品介绍:

产品说明

一般描述

SLK or LOSK is a Ste20-like protein kinase that associates with microtubule and centrosome. Inhibition of SLK activity by dominant-negative mutant or RNAi leads to unfocused microtubule arrangement indicating that SLK is needed for microtubule organization and for the proper localization of Golgi complex. Expression of v-Src can down-regulate SLK activity through the involvement of CK2 which can directly phosphorylate and inhibit SLK activity whereas inhibition of CK2 in v-Src-transformed cells results in normal SLK activity. CK2 and SLK can be co-localized in fibroblasts spreading on fibronectin-coated substrates.

外形

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

制备说明

after opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles

法律信息

PRECISIO is a registered trademark of sigma-aldrich Co. LLC

基本信息

NACRESNA.32

产品性质

重组expressed in baculovirus infected Sf9 cells
产品线PRECISIO® Kinase
测定≥70% (SDS-PAGE)
形式buffered aqueous glycerol solution
specific activity3.9-5.3 nmol/min·mg
分子量 ~180 kDa
NCBI登记号AB002804
运输dry ice
储存温度−70℃
Gene Informationhuman ... SLK(9748)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1

Sigma-Aldrich

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