产品说明
生化/生理作用
Solifenacin succinate (SOL) blocks the cholinergic signals to M3 receptors by inhibiting the muscarinic M3 receptors in the bladder. This action prevents the contractions of the detrusor muscles in the urinary bladder wall, leading to relaxing the bladder as well as decreasing urinary urgency and nocturia. Thus, SOL is a widely used antimuscarinic agent for treating the contraction of the overactive bladder.
基本信息
| 经验(实验)分子式 | C23H26N2O2 · C4H6O4 |
| 分子量 | 480.55 |
| MDL编号 | MFCD00954234 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 旋光性 | [α]/D +35 to +45°, c = 1 in H2O |
| 储存条件 | desiccated |
| 颜色 | white to beige |
| 溶解性 | H2O: 2 mg/mL, clear |
| 储存温度 | 2-8℃ |
| SMILES string | OC(CCC(O)=O)=O.O=C(O[C@H]1CN2CCC1CC2)N3[C@@H](C4=CC=CC=C4)C5=CC=CC=C5CC3 |
| InChI | 1S/C23H26N2O2.C4H6O4/c26-23(27-21-16-24-13-10-18(21)11-14-24)25-15-12-17-6-4-5-9-20(17)22(25)19-7-2-1-3-8-19;5-3(6)1-2-4(7)8/h1-9,18,21-22H,10-16H2;1-2H2,(H,5,6)(H,7,8)/t21?,22-;/m0./s1 |
| InChI key | RXZMMZZRUPYENV-DZSUWJOWSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H361d |
| 预防措施声明 | P201 - P202 - P280 - P308 + P313 - P405 - P501 |
| 危险分类 | Repr. 2 |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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