SU1498

产品名称：

168835-82-3
SU1498
(2E)-2-Cyano-3-[4-hydroxy-3,5-bis(1-methylethyl)phenyl]-N-(3-phenylpropyl)-2-propenamide
Tyrphostin SU1498
(E)-N-(3-Phenylpropyl)-cyano-3,5-diisopropyl-4-hydroxycinnamamide
SU 1498
Tyrphostin SU 1498
AG-1498

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

SU1498 is a potent and selective inhibitor of the VEGFR2 receptor kinase, Flk-1 with an IC₅₀ value of 700 nM. SU1498 is a very weak inhibitor of PDGFR-kinase, EGFR-kinase and HER-2 kinase with IC₅₀ values > 50 μM. SU1498 has been used to study the role of VEGFR2 (Flk-1) in a variety of biological activities including angiogenesis, tumor growth inhibition, and stem cell proliferation.

基本信息

经验(实验)分子式	C₂₅H₃₀N₂O₂
分子量	390.52

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
储存条件	desiccated
颜色	white to beige
溶解性	DMSO: 10 mg/mL, clear
储存温度	−20℃

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable