YN1

产品名称：

75187-63-2
YN1
7,8-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

产品介绍：

产品说明

包装

10, 50 mg in glass bottle

生化/生理作用

YN1 is a potent inhibitor of PFKFB3 (6-Phosphfructo-2-kinase/fructose-2,6-bisphosphatase: IC₅₀ = 670 nM). PFKFB3 is over expressed in many cancers, and catalyzes the production of fructose-2,6-bisphosphate, which can potentiate PFK1 activity, enhancing glycolysis in tumor cells. YN1 inhibits glycolysis and proliferation in HeLa cells.

基本信息

经验(实验)分子式	C₁₅H₁₀O₅
分子量	270.24

产品性质

测定	≥98% (HPLC)
形式	powder
储存条件	desiccated
颜色	white to beige
溶解性	DMSO: 10 mg/mL, clear
储存温度	2-8℃
InChI	1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-15-10(13(11)18)5-6-12(17)14(15)19/h1-7,16-17,19H
InChI key	BMZFZTMWBCFKSS-UHFFFAOYSA-N

安全信息

储存分类代码	6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable