产品说明
应用
Carboxylic acid-poly(ethylene glycol)-b-poly(lactide-co-glycolide) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLGA block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). The carboxylic acid functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.
基本信息
| 线性分子式 | H[(C3H4O2)x(C2H2O2)y]mO[C2H4O]nC2H3O2 |
产品性质
| 形式 | powder or chunks |
| 投料比 | lactide:glycolide 50:50 |
| 分子量 | PEG average Mn 5,000 (by NMR) PLGA average Mn 20,000 (by NMR) |
| 颜色 | white to tan |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
