产品说明
一般描述
The FAS receptor (FasR) is a protein encoded by the TNFRSF6 gene in humans and is mapped to chromosomal band 10q24.1. It is a cell surface antigen expressed on a variety of normal and malignant cells.
免疫原
Recombinant tumor necrosis factor receptor superfamily, member 6 isoform 1
Immunogen Sequence: GI # 4507583, sequence 21-165
应用
Anti-FAS (ab1) antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生化/生理作用
The FAS receptor (FasR) is associated with programmed cell death (apoptosis). It functions as an apoptosis-signaling cell surface Ag. Mutation of the gene or defective FAS signaling may render the T-cell lymphoblastic lymphomas (T-LBLs) tumor cells resistant to apoptotic cell death.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
MDL编号 | MFCD00283209 |
产品性质
生物来源 | chicken |
质量水平 | 200 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
species reactivity | mouse, human, rat |
manufacturer/tradename | Genway 15-288-22766 |
technique(s) | western blot: suitable |
NCBI登记号 | NP_000034.1 |
UniProt登记号 | P25445 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... FAS(355) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
Sigma-Aldrich