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位置:首页 > 品牌 > Sigma-Aldrich > Anti-14-3-3 η Antibody

Anti-14-3-3 η Antibody

品牌
Sigma-Aldrich
货号
AB9736
规格纯度
serum, Chemicon®
参考价格
6190.47 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-14-3-3 η Antibody
产品介绍:

产品说明

一般描述

Mammals express seven distinct 14-3-3 isoforms (gamma, epsilon, beta, zeta, sigma, eta, tau) that form multiple homo- and hetero- dimmers, thus rendering 14-3-3 as a key multifunctional regulatory molecule. 14-3-3 isomers have been implicated in several neurological disorders: for example isoforms gamma, epsilon and beta are expressed in the cerebrospinal fluid of Creutzfeldt-Jakob patients, but not patients suffering from other neurological conditions such as Alzheimer′s.

The 14-3-3 eta antibody is one of a panel of antibodies that were generated against 14-3-3 isoforms and have demonstrated their potential for use as an ELISA-based diagnostic tool. These antibodies will allow the research to investigate the role of this protein in key cellular processes and neurological disorders such as Creutzfeldt-Jakob, Alzheimer′s and Parkinson′s Disease.

特异性

14-3-3 eta. By Western blot the antibody recognizes the ~30 kDa protein.

免疫原

Synthetic peptide from the N-terminal area of sheep 14-3-3 eta.

应用

Western blot: 1:3,000 using ECL.
Immunohistochemistry: 1:1,600-1:3,200 on mouse brain tissue which was treated by hydrated autoclaving at 121°C for 15 minutes prior to immunolabeling. Endogenous peroxidase was blocked with hydrogen peroxide in methanol and non-specific labeling with normal goat serum at 1:20 for 5 minutes.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Anti-14-3-3 η Antibody detects level of 14-3-3 η & has been published & validated for use in WB, IH.

外形

Serum
Liquid.

储存及稳定性

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container′s cap.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

生物来源rabbit
质量水平100
抗体形式serum
antibody product typeprimary antibodies
克隆polyclonal
species reactivitysheep, rabbit, chicken, human, rat, mouse, bovine
manufacturer/tradenameChemicon®
technique(s)immunohistochemistry: suitable
western blot: suitable
NCBI登记号NM_003405.3
UniProt登记号Q04917
运输dry ice
Gene Informationhuman ... YWHAH(7533)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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