产品说明
免疫原
Immunogen Sequence: GI # 4501913, sequence 72-144
Recombinant ADAM metallopeptidase domain 23 preproprotein
应用
Anti-ADAM23 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生化/生理作用
Disintegrin and metalloproteinase domain-containing protein 23 is an enzyme encoded by the ADAM23 gene in humans and is a member of a disintegrin and metalloprotease (ADAM) family. It is higly expressed in the brain and may function as integrin ligands in the brain along with other proteins. ADAM23 is associated with the progression of non-small-cell lung carcinoma (NSCLC) and its downregulation may be correlated with promoter methylation. It may be down-regulated by aberrant promoter hypermethylation during the progression of colorectal cancer. ADAM23 is down-regulated by methylation in brain tumors, which is a rare event.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | chicken |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| species reactivity | human |
| manufacturer/tradename | Genway 15-288-21429 |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_003803.1 |
| UniProt登记号 | O75077 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... ADAM23(8745) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
Sigma-Aldrich
m.cnreagent.com
