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Anti-CEACAM1 Antibody, clone 4D1/C2

品牌
Sigma-Aldrich
货号
MABT65
规格纯度
clone 4D1/C2, from mouse
参考价格
6022.61 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-CEACAM1 Antibody, clone 4D1/C2
Carcinoembryonic antigen-related cell adhesion molecule 1, Biliary glycoprotein 1, BGP-1, CD66a
产品介绍:

产品说明

一般描述

CEACAM1 (carcinoembryonic antigen-related cell adhesion molecule 1) is thought to be a member of the immunoglobulin superfamily and is known as an epithelial tumor suppressor and an angiogenic growth factor. It has also been linked to the actin-based cytoskeleton. CEACAM1 is also known as a cellular receptor for a number of human mucosa pathogenic bacteria. The loss of activity of CEACAM1 has been related to the development of colorectal cancer.

免疫原

Recombinant protein corresponding to human CEACAM1.
Epitope: Unknown

应用

Research Category
Cell Structure
Immunohistochemistry Analysis: A representative lot was used by an independent laboratory to detect CEACAM1 in non-small-cell lung cancer (Dango, S., et al. (2008). Lung Cancer. 60:426-433).

Western Blot Analysis: A representative lot was used by an independent laboratory to detect CEACAM1 in human granulocyte lysate (Bogoevska, V. et al., (2006). Glycobiology. 16(3): 197–209).

Flow Cytometry Analysis: A representative lot was used by an independent laboratory to detect CEACAM1 in human granulocytes by FACS analysis (Bogoevska, V. et al., (2006). Glycobiology. 16(3): 197–209).
Detect CEACAM1 using this Anti-CEACAM1 Antibody, clone 4D1/C2 validated for use in WB, IH.
Research Sub Category
Adhesion (CAMs)

质量

Evaluated by Western Blot in HepG2 cell lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected CEACAM1 in 10 µg of HepG2 cell lysate.

目标描述

~150 kDa observed.
Bands are usually observed at ~120-160 kDa, resulting from different glycosylations (Lauke, H., et al. (2004). Mol. Hum. Reprod. 10(4):247-252).

外形

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
HepG2 cell lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

质量水平100
生物来源mouse
抗体形式purified antibody
antibody product typeprimary antibodies
克隆4D1/C2, monoclonal
species reactivityhuman
technique(s)ELISA: suitable
flow cytometry: suitable
immunohistochemistry: suitable
western blot: suitable
同位素/亚型IgG1κ
NCBI登记号NP_001020083
UniProt登记号P13688
运输wet ice

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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