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位置:首页 > 品牌 > Sigma-Aldrich > Anti-Dopamine D2 receptor (DRD2) Antibody, clone 2B9

Anti-Dopamine D2 receptor (DRD2) Antibody, clone 2B9

品牌
Sigma-Aldrich
货号
MABN53
规格纯度
clone 3D9, from mouse
参考价格
5854.74 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-Dopamine D2 receptor (DRD2) Antibody, clone 2B9
Dopamine D2 receptor
产品介绍:

产品说明

一般描述

Problems in the CNS dopaminergic system are thought to be the root cause of some neuropsychiatric disorders. Dopamine D2 receptor is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Dopamine D2 receptor signaling using Nurr1 and ERK may play an important role in mesencephalic dopaminergic neuronal development. Faulty D2 receptors have been common in cases of ROS-dependent hypertension. In addition, defects in DRD2 are associted with alcohol-responsive dystonia, varying susceptability to familial alcoholism as well as a contributing factor to the suicide risk in alcoholics.

免疫原

Linear peptide corresponding to human Dopamine D2 receptor.

应用

Immunocytochemistry Analysis: A previous lot was used by an independent laboratory to detect Dopamine D2 receptor in Ntera-2 cells and in rat brain neurons. Courtesy of Glenn Morris, Wolfson Centre for Inherited Neuromuscular Disease.
This Anti-Dopamine D2 receptor (DRD2) Antibody, clone 2B9 is validated for use in WB, IC for the detection of Dopamine D2 receptor (DRD2).

质量

Evaluated by Western Blot in rat spinal cord tissue lysate.

Western Blot Analysis: 5 µg/mL of this antibody detected Dopamine D2 receptor on 10 µg of rat spinal cord tissue lysate.

目标描述

~50 kDa observed

外形

CHT Ion exchange
Format: Purified

分析说明

Control
Rat spinal cord tissue lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

质量水平100
生物来源mouse
抗体形式purified antibody
antibody product typeprimary antibodies
克隆3D9, monoclonal
species reactivityrat
species reactivity (predicted by homology)human (immunogen homology)
technique(s)immunocytochemistry: suitable
western blot: suitable
同位素/亚型IgMκ
NCBI登记号NP_000786
UniProt登记号P14416
运输wet ice

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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