产品说明
免疫原
Immunogen Sequence: GI # 21361340, sequence 21-36
Synthetic peptide sequence of glycogen synthase kinase 3β.
应用
Anti-GSK3β antibody produced in chicken is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生化/生理作用
Glycogen synthase kinase 3β is an enzyme encoded by the GSK3B gene in humans. It is closely related to protein-serine kinases and acts as an inhibitory component of Wnt signalling during embryonic development, and cell proliferation in adult tissues. GSK-3β helps in facilitating NF-κB function. It is a key endogenous factor for specifically regulating oligodendrogenesis. The genotypes may interact with major depressive disorder (MDD). GSK-3β is a proline-directed kinase that helps in forming part of the wingless signaling pathway.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
MDL编号 | MFCD01633410 |
NACRES | NA.41 |
产品性质
生物来源 | chicken |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
species reactivity | mouse, human, rat |
manufacturer/tradename | Genway 15-288-22779 |
technique(s) | indirect ELISA: suitable western blot: suitable |
NCBI登记号 | NP_002084.2 |
UniProt登记号 | P49841 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... GSK3B(2932) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
Sigma-Aldrich