产品说明
一般描述
Integrins are transmembrane proteins that are involved in interactions cell-to-cell and cell-to-extracellular matrix (ECM) adhesion. Integrins play diverse roles including cell migration, development, wound healing, differentiation, and apoptosis. Integrin alpha 10 subunit (ITGA10), along with integrin beta 1, is thought to be an essential part of a novel collagen type II receptor expressed mainly in chondrocytes and cartilage tissue.
特异性
This antibody recognizes the extracellular domain of Integrin alpha 10.
Other homologies: rat (93% sequence homology).
免疫原
Epitope: Extracellular Domain
KLH-conjugated linear peptide corresponding to the extracellular domain of human Integrin alpha-10.
应用
Research Category
Cell Structure
Research Sub Category
Integrins
Adhesion (CAMs)
Detect Integrin alpha 10 (ITGA10) using this Anti-Integrin alpha 10 (ITGA10) Antibody validated for use in WB.
质量
Evaluated by Western Blot in SW-1353 cell lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected integrin alpha10 in 10 µg of SW-1353 cell lysate.
目标描述
~127 kDa observed
外形
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
SW-1353 cell lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | human, primate, rhesus macaque |
species reactivity (predicted by homology) | pig (based on 100% sequence homology), rhesus monkey (based on 100% sequence homology), chimpanzee (based on 100% sequence homology), canine (based on 100% sequence homology) |
technique(s) | western blot: suitable |
NCBI登记号 | NP_003628 |
UniProt登记号 | O75578 |
运输 | wet ice |
Gene Information | human ... ITGA10(8515) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich