产品说明
一般描述
Members of the evolutionarily conserved Mastermind (MAM) protein family, including the three related mammalian Mastermind-like (MAML) proteins MAML1–3, function as crucial coactivators of Notch-mediated transcriptional activation. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.
特异性
Reactivity with other species has not been tested.
Cat. # AB15546 recognizes MAML1 protein.
免疫原
Synthetic Linear Peptide.
应用
This Anti-MAML1 Antibody is validated for use in WB for the detection of MAML1.
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience
MAML1 can be detected at 1/1000 dilution in 10 µg of HEK293 cell Lysate.
质量
Routinely evaluated by immunoblot.
目标描述
108 kDa
外形
Serum with 0.05% NaN3
储存及稳定性
Maintain at -20°C in undiluted aliquots for up to 1 year after date of receipt.
分析说明
Control
Tested by Western Blot on HEK293 cell lysate.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | serum |
antibody product type | primary antibodies |
克隆 | polyclonal |
species reactivity | human |
manufacturer/tradename | Chemicon® |
technique(s) | western blot: suitable |
UniProt登记号 | Q92585 |
运输 | wet ice |
Gene Information | human ... MAML1(9794) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 1 |
Sigma-Aldrich