Anti-NKAP antibody produced in chicken

产品说明

免疫原

Immunogen Sequence: GI # 13375676, sequence 110-170
Recombinant NF-kappaB activating protein

应用

Anti-NKAP antibody produced in chicken is suitable for western blottinganalysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

NF-κ-B-activating protein is a protein encoded by the NKAP gene in humans. It is a novel nuclear regulator of TNF- and IL-1-induced NF-κB activation. NKAP is associated with the histone deacetylase HDAC3 and is found to be a part of DNA-binding complex. It is associated with the Notch corepressor complex. NKAP functions as a transcriptional repressor, acts on Notch target genes and is essential for αβ T cell development. It is also required for T cell maturation and the acquisition of functional competency.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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