产品说明
一般描述
SRP54 (signal recognition particle 54kDa) is a component of the cytoplasmic ribonucleoprotein complex called SRP. It functionally contains an N-terminal, a central G-domain and an M-domain rich in methionine. It has the SRP19 binding region in its 6 and 8 helices.
免疫原
Recombinant signal recognition particle 54kDa
Immunogen Sequence: GI # 4507215, sequence 300-504
应用
Anti-SRP54 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生化/生理作用
Protein SRP54 serves to recognize, bind and transport proteins for the membrane or secretion. The methionine-rich M-domain of protein SRP54 (SRP54M) binds to SRP RNA and the signal peptide as protein emerges from the ribosome. It interacts with nascent signal peptide and SRP RNA. SRP54 helps in regulating the targeted secretory and membrane proteins to the endoplasmic reticulum (ER).
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
基本信息
| MDL编号 | MFCD02264112 |
| NACRES | NA.41 |
产品性质
| 生物来源 | chicken |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| species reactivity | rat, mouse, human |
| manufacturer/tradename | Genway 15-288-21244 |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_003127.1 |
| UniProt登记号 | P61011 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... SRP54(6729) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
Sigma-Aldrich
m.cnreagent.com
