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Anti-Tbr1 Antibody

品牌
Sigma-Aldrich
货号
AB2261
规格纯度
from chicken, purified by affinity chromatography
参考价格
6694.05 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-Tbr1 Antibody
T-box, brain, 1
产品介绍:

产品说明

一般描述

Tbr1 gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Tbr1, a putative transcription factor known to be expressed in post-mitotic neurons, has been found highly expressed in glutamatergic early-born cortical neurons. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region the Tbr1 derived protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.

特异性

This antibody recognizes Tbr1.

免疫原

Epitope: Internal
KLH-conjugated linear peptide corresponding to mouse Tbr1.

应用

Immunohistochemistry Analysis: 1:100 dilution from a previous lot detected Tbr1 in mouse frontal cortex tissue.
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience
Anti-Tbr1 Antibody is an antibody against Tbr1 for use in WB, IH.

质量

Evaluated by Western Blot in human fetal brain tissue lysate.

Western Blot Analysis: 0.025 µg/ml of this antibody detected Tbr1 on 10 µg of human fetal brain tissue lysate.

目标描述

~ 68 kDa is observed; however, UniProtKB/Swiss-Prot entry Q64336 (TBR1_MOUSE) lists a mass of 73.941 kDa

外形

Affinity purified
Purified chicken polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Human fetal brain tissue lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

生物来源chicken
质量水平100
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
纯化方式affinity chromatography
species reactivitymouse, human, rat
species reactivity (predicted by homology)opossum (based on 100% sequence homology), bovine (based on 100% sequence homology), horse (based on 100% sequence homology), canine (based on 100% sequence homology), pig (based on 100% sequence homology)
technique(s)immunohistochemistry: suitable
western blot: suitable
NCBI登记号NP_033348
UniProt登记号Q64336
运输wet ice

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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