产品说明
一般描述
Thymosin beta-4 is the most prevalent of the cytoplasmic G-actin binding proteins belonging to the highly conserved thymosin beta family. Known to bind actin monomers, Thymosin beta-4 sequesters G-actin in a manner that prevents actin polymerization. Thymosin beta-4 plays several important roles including induction of tissue remodeling, wound healing in both cell and tissue injuries, and cell differentiation via mechanisms that have yet to be fully elucidated. It is involved in the regulation of the cytoskeleton, and thereby influences an array of cellular processes. Within the brain, Thymosin beta-4 is associated with the neurite extension and migration of neurons. Expression has been observed in various hemopoietic and lymphoid malignant cell lines.
特异性
Th antibody recognizes the internal domain of Thymosin beta-4.
免疫原
GST-tagged recombinant protein corresponding to the internal domain of human Thymosin beta-4.
应用
Anti-Thymosin beta-4 Antibody is an antibody against Thymosin beta-4 for use in WB & IC.
Western Blot (Snap i.d.
Immunocytochemistry Analysis: 1:500 dilution from a previous lot detected Thymosin beta-4 in NIH/3T3, HeLa, and A431 cells.
质量
Evaluated by Western Blot in recombinant Thymosin beta-4.
Western Blot Analysis: 1 µg/mL of the antibody detected Thymosin beta-4 on 10 µg of recombinant Thymosin beta-4.
目标描述
~ 33kDa observed
外形
Affinity purified
分析说明
Control
Recombinant Thymosin beta-4
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | human, mouse |
species reactivity (predicted by homology) | rat (based on 100% sequence homology) |
technique(s) | immunocytochemistry: suitable western blot: suitable |
NCBI登记号 | NP_066932 |
UniProt登记号 | P62328 |
运输 | wet ice |
Gene Information | human ... TMSB4X(7114) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich