Calmodulin, His·Tag^® Human, Recombinant

产品说明

一般描述

Full-length, recombinant human calmodulin fused to a His•Tag sequence at the N-terminus. Contains four functional Ca²⁺-binding sites (aa 20-31; aa 56-67; aa 93-104; aa 129-140) with EF-hands (aa 7-42; aa 43-78; aa 80-115; aa 116-148); and a ubiquitination site at Lys²¹. This preparation is qualified for use as a substrate for protein tyrosine kinases in in vitro assays. Through its interaction with Ca²⁺, calmodulin mediates the control of a large number of enzymes, including protein kinases and phosphatases. It is expected to be phosphorylated at Thr⁴⁴ by CaMK4. In addition, it serves as a substrate for various protein tyrosine kinases.

包装

50 μg in Plastic ampoule
Please refer to vial label for lot-specific concentration.

警告

Toxicity: Standard Handling (A)

外形

In PBS, 0.2% Protease Inhibitor Cocktail Set VII (Cat. No. 539138).

重悬

Following initial thaw, aliquot and freeze (-70°C).

其他说明

Chou, J.J., et al. 2001.Nat. Struct. Biol.8, 990.
Lennon, G., et al. 1996.Genomics33, 151.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
HIS TAG is a registered trademark of Merck KGaA, Darmstadt, Germany

产品性质

安全信息