<i>N</i>-Methylated pomalidomide

产品名称：

1352827-50-9
N-Methylated pomalidomide
Ligand for PROTAC research
E3 Ligase ligand methylated negative control
4-Amino-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

产品介绍：

产品说明

应用

N-Methylated pomalidomide is a ligand used as a negative control for pomalidomide (P0018) in the recruitment of the Cereblon (CRBN) protein for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology.

其他说明

Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation

Portal: Building PROTAC^® Degraders for Targeted Protein Degradation

Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4

Targeted Protein Degradation by Small Molecules

Small-Molecule PROTACS: New Approaches to Protein Degradation

法律信息

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

基本信息

经验(实验)分子式	C₁₄H₁₃N₃O₄
分子量	287.27
NACRES	NA.22

产品性质

质量水平	100
测定	≥98%
形式	powder or crystals
运输	wet ice
储存温度	2-8℃
SMILES string	O=C(C(CC1)N(C2=O)C(C3=C2C=CC=C3N)=O)N(C)C1=O

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable