NanoFabTx^TM PEG-PLA drug formulation screening kit

产品说明

一般描述

This kit minimizes laboratory setup with optimized protocols and step-by-step instructions for synthesizing drug-encapsulated nanoparticle-based formulations.

Protocols for two different particle synthesis methods are included.

• A Nanoprecipitation protocol to prepare drug-encapsulated nanoparticles in standard laboratory glassware.
• A Microfluidics protocol using commercial platforms or syringe pumps.

The microfluidics protocol uses NanoFabTx^™ device kits (911593), which provide all the microfluidics chips, fittings, and tubing required to get started with microfluidics-based synthesis (compatible microfluidics system or syringe pump required).

应用

NanoFabTx^™ PEG-PLA drug formulation screening kit is designed for maximizing the encapsulation of hydrophobic drugs in specifically sized, biodegradable, PEGylated PLA nanoparticles for drug delivery research applications. The kit contains rationally selected PEGylated PLA polymers that have been widely used in drug delivery systems for controlled drug release of many different types of therapeutic molecules. NanoFabTx^™ nanoformulation reagent kits enable users to encapsulate a wide variety of therapeutic drug molecules for targeted or extended drug delivery without the need for lengthy trial-and-error optimization. NanoFabTx^™ kits provide an easy-to-use toolkit for encapsulating a variety of therapeutics in nanoparticles, microparticles, or liposomes. Drug encapsulated particles synthesized with the NanoFabTx^™ kits are suitable for biomedical research applications such as oncology, immuno-oncology, gene delivery, and vaccine delivery.

特点和优势

• Ready-to-use nanoformulation kit for PEGylated nanoparticles
• Choose from nanoprecipitation or microfluidics-based protocols
• Create specifically sized, biodegradable, PEGylated PLA nanoparticles
• Maximize the encapsulation of hydrophobic drugs
• Two different PEGylated PLAs are included
• Optimized for 60 nm-100 nm nanoparticles

For more information, please refer to the protocol under the document section of this page.

法律信息

NANOFABTX is a trademark of sigma-aldrich Co. LLC

产品性质

描述	Kit components : PEGPLA-L-M (919942-500mg) PEGPLA-H-M (919934-500mg) Stabilizer-Nano (907766-5g) PEG-PLA drug formulation screening kit, for synthesis of PEGylated PLA nanoparticles
储存温度	2-8℃

安全信息

储存分类代码	10 - Combustible liquids
WGK	WGK 3