Anti-CRHR2 antibody produced in mouse

产品说明

一般描述

CRHR2 (corticotropin releasing hormone receptor 2) gene is located in human chromosome 7p14.3. The encoded protein is a G-coupled protein receptor that belongs to the family of corticotropin releasing factor (CRF). The gene is widely expressed in the peripheral organs such as the heart, skeletal muscle, intestines and airway epithelium.

免疫原

CRHR2 (NP_001874.2, 1 a.a. ~ 411 a.a) full-length human protein.

Sequence
MDAALLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTCWPRSAAGALVERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDKQRKYDLHYRIALVVNYLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESNEVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIVAWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYCFFNGEVRSAVRKRWHRWQDHHSLRVPMARAMSIPTSPTRISFHSIKQTAAV

生化/生理作用

CRHR2 (corticotropin releasing hormone receptor 2) is known to control immune responses and stress hormone system, especially the local peripheral inflammatory responses. In brain, activation of CRHR2 is believed to reduce anxiety.

外形

Solution in phosphate buffered saline, pH 7.4

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

产品性质

安全信息