产品说明
一般描述
Epidermal growth factor (EGF) module-containing mucin-like receptor 2 (EMR2) is also called as ADGRE2 (adhesion G protein-coupled receptor E2). It contains an N-terminal extracellular region that consists of five tandem EGF-like adhesion domains, an internal mucin-like stalk domain containing a short G-protein proteolytic site and a C-terminal seven-pass transmembrane domain. EMR2 is abundantly expressed in myeloid leukocytes and on the surface of lung mast cells. It is located on human chromosome 19p13.
Anti-EMR2 Antibody detects endogenous levels of total EMR2 protein.
免疫原
The antiserum was produced against synthesized peptide derived from human EMR2.
Immunogen Range: 765-814
生化/生理作用
Epidermal growth factor (EGF) module-containing mucin-like receptor 2 (EMR2) acts as a diagnostic biomarker for sepsis and systemic inflammation. Overexpression of EMR2 shows poor poor survival rate in glioblastoma patients.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen 90 kDa |
| species reactivity | human |
| 浓度 | ~1 mg/mL |
| technique(s) | ELISA: 1:20000 immunofluorescence: 1:100-1:500 western blot: 1:500-1:1000 |
| NCBI登记号 | Q9UHX3 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... EMR2(30817) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
