产品说明
一般描述
Epstein-Barr BGLF4 plays many key roles by phosphorylating several proteins including the viral DNA processivity factor BMRF1, EBNA1 or EBNA2. It is required for efficient lytic DNA replication and release of nucleocapsids from the nucleus. This protein contributes to the compaction of host cell chromatin in cells undergoing lytic replication, presumably by phosphorylating the host condensin complex and host TOP2A. BGLF4 induces disassembly of the nuclear lamina by phosphorylating with host LMNA, and phosphorylates substrates involved in capsid assembly and DNA packaging. It facilitates the switch from latent to lytic DNA replication by down-regulating EBNA1 replication function. This protein phosphorylates the viral immediate-early protein BZLF1.
免疫原
BGL (1-30)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of Epstein-Barr BGLF4 Kinase.
外形
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 200 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| species reactivity | Epstein-Barr virus |
| technique(s) | indirect ELISA: 1:1000 |
| NCBI登记号 | YP_401688 |
| UniProt登记号 | P13288 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
