产品说明
一般描述
T-cell leukemia homeobox 2 (TLX2) is a transcription factor involved in mouse enteric nervous system development. It functions as a transcriptional target of PHOX2B in neural crest-derived cells. PHOX2B-TLX2 promoter interactions have been implicated in neuronal differentiation during human embryogenesis. Loss-of-function mutation in TLX2 has been implicated in gastrointestinal stromal tumor (GIST).
Rabbit Anti-TLX2 antibody recognizes human, mouse, rat, canine, and zebrafish TLX2.
免疫原
Synthetic peptide directed towards the C terminal region of human TLX2
应用
Rabbit Anti-TLX2 antibody is suitable for western blot (2.5 μg/ml) and immunohistochemistry (4-8 μg/ml) applications.
生化/生理作用
TLX2 contains 1 homeobox DNA-binding domain
序列
Synthetic peptide located within the following region: QQDALPRPLRPPLPPDPLCLHNSSLFALQNLQPWAEDNKVASVSGLASVV
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 30 kDa |
| species reactivity | dog, rabbit, guinea pig, human, mouse, bovine, rat |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI登记号 | NP_057254 |
| UniProt登记号 | O43763 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... TLX2(3196) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
