纯度规格:Cell-permeable inhibitor of gp130. Binds to gp130 and induces its phosphorylation at Ser782 in ovarian cancer cells. Suppresses constitutive phosphorylation of and nuclear translocation of Stat3.
纯度规格:A cell-permeable compound that competitively binds to Hu antigen R (HuR; Ki = 350 nM) and disrupts the interaction of HuR and adenine- and uridine-rich element (ARE) of target mRNAs.
纯度规格:A cell-permeable, fast acting, branched polyamine. Induces growth of actin-enriched lamellipodia within minutes without the need for serum cofactors .
纯度规格:A cell-permeable. Reversible, selective inhibitor of the growth of malignant peripheral nerve sheath tumors (EC50 = 439 nM, 754 nM, and 1.0 μM in S462, SNF96.2, and sMPNST cells).
纯度规格:A cell-permeable myristoylated hexapeptide that selectively inhibits integrin outside-in signaling without affecting inside-out signaling. Blocks the interaction of Gα3 and integrin β3 subunit.
纯度规格:A cell-permeable compound that selectively downregulates the expression of p21 (~10 μM), independent of p53.expression, at either transcription or post-transcriptional level.