Furin Substrate, Fluorogenic-Calbiochem

产品说明

一般描述

A fluorogenic substrate for furin, a mammalian homolog of the yeast Kex2 endoprotease (k_cat/K_m ~ 2 x 10⁴ s^-1M^-1).
A fluorogenic substrate for furin (k_cat/K_m ~2 X 10⁴ M^-1 s^-1), a mammalian homolog of the yeast Kex2 endoprotease. Also serves as a substrate for related protein, prohormone convertase 2 (PC2) (k_cat/K_m ~6 X 10³ M^-1 s^-1). Excitation max: ~360-380 nm; emission max: ~430-460 nm).

包装

5 mg in Plastic ampoule

生化/生理作用

Primary Target
Fluorogenic substrate for furin
kcat/Km ~ 2 x 104 s-1M-1 for furin
Product does not compete with ATP.
Reversible: no
Cell permeable: no

警告

Toxicity: Standard Handling (A)

序列

Pyr-Arg-Thr-Lys-Arg-AMC

外形

Supplied as a trifluoroacetate salt.

重悬

Following reconstitution, aliquot and freeze (-20°). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Lamango, N.S., et al. 1996. Arch. Biochem. Biophys.330, 238.
Hatsuzawa, K., et al. 1992. J. Biol. Chem. 267, 16094.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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