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Anti-Interferon-γ antibody produced in goat

品牌
Sigma-Aldrich
货号
I9016
规格纯度
IgG fraction of antiserum
参考价格
4731.57 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-Interferon-γ antibody produced in goat
Anti-IFN-γ
产品介绍:

产品说明

一般描述

Interferons (IFNs) are cytokines that are secreted in response to viral or bacterial infections and tumorigenesis. There are two types of IFNs, type I (IFN-α and IFN-β) and type II (IFN-γ). IFN-γ binds to specific receptor complex consisting of IFNγR1 and IFNγR2. There are many pathways that are mediated by IFN-γ binding such as JAK/STAT1, AP-1, NF-κB, STAT3 and STAT5. IFN-γ is pleotropic and performs various functions related to immune response, inflammation, differentiation and activation of T cells, cell cycle and apoptosis. The most studied function of IFN-γ is priming the antigen presenting cells by upregulating major histocompatibility (MHC) Class I molecules. IFN-γ has clinical applications in autoimmune diseases (rheumatoid arthritis), multiple sclerosis, cancer, HIV and fungal infections
Anti-Interferon-γ recognizes human Interferon-γ. It does not bind specifically to mouse, hamster or bovine IFN-γ.

特异性

The antibody shows no cross-reactivity with recombinant mouse IFN-γ.

免疫原

recombinant human IFN-γ.

应用

Anti-interferon-γ antibody may be used for immunoblotting at a working concentration of 1-2 μg/ml. The antibody is suitable for neutralization reactions.

外形

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

EC 号202-739-6
MDL编号MFCD00162308
NACRESNA.41

产品性质

质量水平100
生物来源goat
抗体形式IgG fraction of antiserum
antibody product typeprimary antibodies
克隆polyclonal
species reactivityhuman
technique(s)neutralization: suitable
western blot: suitable
UniProt登记号P01579
储存温度−20℃
Gene Informationhuman ... IFNG(3458)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)

Sigma-Aldrich

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