产品说明
一般描述
IL-12 also known as Natural Killer Cell Stimulatory Factor (NKSF) is a 75kD protein that belongs to type I cytokine receptor family and is produced mainly by monocytes and NK cells. IL-12 signals with the help of IL-12 receptor made up of two subunits designated β1 and β2. Interleukin-12 receptor subunit β-1 binds interleukin-12 with low affinity and facilitates in IL12 transduction. Anti-interleukin-12 receptor β1 antibody can be used in ELISA (0.5-1.0 μg/mL) using recombinant human IL-12 Rβ1. Goat anti-interleukin-12 receptor β1 antibody has shown 5% (approx.) cross-reactivity with recombinant mouse IL-12 Rβ1.
特异性
The antibody shows 5% cross-reactivity with recombinant mouse IL-12 Rβ1.
免疫原
recombinant human IL-12 Rβ1 extracellular domain, expressed in NSO cells
应用
Anti-interleukin-12 receptor β1 antibody can be used in immunoblotting for localization and detection of recombinant human IL-12 Rβ1.
外形
Lyophilized from 0.2 μm filtered solution of phosphate buffered saline
基本信息
| MDL编号 | MFCD01633525 |
产品性质
| 质量水平 | 100 |
| 生物来源 | goat |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | lyophilized powder |
| species reactivity | human |
| technique(s) | indirect ELISA: 0.5-1.0 μg/mL using recombinant human IL-12 Rβ1 western blot: 0.1-0.2 μg/mL using recombinant human IL-12 Rβ1 |
| UniProt登记号 | P42701 |
| 储存温度 | −20℃ |
| Gene Information | human ... IL12RB1(3594) |
Sigma-Aldrich
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