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Anti-LPA1, C-Terminal antibody produced in rabbit

品牌
Sigma-Aldrich
货号
E5017
规格纯度
IgG fraction of antiserum, buffered aqueous solution
参考价格
4731.57 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-LPA1, C-Terminal antibody produced in rabbit
Anti-Endothelial Cell Differentiation Gene 2
Anti-EDG-2
产品介绍:

产品说明

免疫原

synthetic peptide corresponding to amino acids 328-344 of human EDG-2/LPA1.

应用

Anti-LPA1, C-Terminal antibody produced in rabbit is suitable for western blotting at a working dilution of 1:1000 using rat brain microsomal fraction.

生化/生理作用

Lysophosphatidic acid receptor 1 (LPA1) is a protein encoded by the LPAR1 gene in humans. It is constitutively localized in the nucleus of mammalian cells and may be involved in regulating intranuclear protein phosphorylation and signalling. LPA1 is differentially expressed in androgen-insensitive and LPA-responsive cells. It is not expressed in androgen-dependent and LPA-resistant cells.Its expression is significantly higher in the cancer compared with the benign tissues and may possibly act as a drug target to interfere with progression of prostate cancer. LPA1 helps in promoting cell proliferation, survival and migration by acting on cognate G protein-coupled receptors.

外形

Solution in PBS with 0.08% sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD02686119
NACRESNA.41

产品性质

生物来源rabbit
质量水平200
偶联物unconjugated
抗体形式IgG fraction of antiserum
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen ~50 kDa
species reactivityrat, human
technique(s)western blot: suitable
UniProt登记号Q92633
运输dry ice
储存温度−20℃
Gene Informationhuman ... LPAR1(1902)
rat ... Lpar1(116744)

Sigma-Aldrich

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