产品说明
一般描述
Extracellular Signal-Regulated Kinases (ERKs) are proteins that belong to mitogen-activated protein kinase superfamily (MAPK) and have a pivotal role in cell cycle, differentiation, transcription and learning and memory through signal transduction in the cytoplasm and the nucleus. ERK5 MAP kinase cascade has a crucial functions like- induction of special form of cardiac hypertrophy, enhanced neuronal survival and early steps of muscle cell differentiation. Anti-phospho-ERK5 (pThr218/pTyr220) antibody can be used in immunostaining. Rabbit anti- phospho-ERK5 (pThr218/pTyr220) antibody reacts specifically with ERK5 (88 kD) of human.
免疫原
Synthetic phosphopeptide derived from the region of human ERK5 that contains threonine 218 and tyrosine 220. This sequence is conserved in human and mouse.
应用
Each vial contains enough material for 10 blots. The end user should determine the correct working dilution for their process.
外形
Solution in Dulbecco′s PBS, pH 7.3, with 50% glycerol, 1 mg/ml BSA and ≤ 0.1% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
EC 号 | 200-289-5 |
MDL编号 | MFCD01633332 |
NACRES | NA.44 |
产品性质
生物来源 | rabbit |
质量水平 | 200 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous glycerol solution |
species reactivity | human |
UniProt登记号 | Q13164 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... MAPK7(5598) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
Sigma-Aldrich