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Anti-phospho-GATA4 (pSer105) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
G8044
规格纯度
affinity isolated antibody, buffered aqueous solution
参考价格
4731.57 *本价格含增值税费
促销
服务
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数量
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产品名称:
Anti-phospho-GATA4 (pSer105) antibody produced in rabbit
产品介绍:

产品说明

免疫原

Anti-phospho-GATA4 (pSer105) antibody produced in rabbit is suitable for western blotting at working dilution 1:500.
synthetic phosphopeptide derived from the region of GATA-4 that contains serine 105.

生化/生理作用

GATA-4 has a molar mass of 46kDa and belongs to the GATA family of zinc finger-containing transcription factors. It is involved in the development of cardiac hypertrophy and remodeling. It plays a crucial role in regulating basal and agonist or stress-induced gene expression in cardiac and smooth muscle cell types. Upon agonist stimulation via MEK1-ERK1/2, and weakly via JNK or p38 MAPKs, Ser105 of GATA-4 is phosphorylated. Phosphorylation of GATA-4 by hepatocyte growth factor facilitates cell survival in cardiac muscle cells via MEK/ERK-dependent signaling pathway.

外形

Solution in Dulbecco′s PBS, pH 7.3 with 1 mg/mL BSA and 0.05% Sodium Azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD06798487
NACRESNA.41

产品性质

生物来源rabbit
质量水平200
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen 46 kDa
species reactivitymouse
包装pkg of (1 vl = 100ul)
technique(s)western blot: 1:500
UniProt登记号Q08369
运输dry ice
储存温度−70℃
Gene Informationhuman ... GATA4(2626)
mouse ... Gata4(14463)
rat ... Gata4(54254)

Sigma-Aldrich

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