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Anti-Interleukin-8 antibody produced in goat

品牌
Sigma-Aldrich
货号
I8026
规格纯度
affinity isolated antibody, lyophilized powder
参考价格
6871.47 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-Interleukin-8 antibody produced in goat
Anti-IL-8
Anti-CXCL8
产品介绍:

产品说明

一般描述

Interleukin 8 (IL-8) is an 8kD, 72 amino acid residue containing cytokine that belongs to C-X-C chemokine family . The IL-8 gene is mapped to human chromosome 4q13.3.

特异性

The antibody will neutralize the biological activity of recombinant and natural human IL-8, but not recombinant human GROα.

免疫原

recombinant human IL-8 (CXCL8).

应用

Anti-Interleukin-8 antibody can be used in immunocytochemistry and immunohistochemistry.
Anti-Interleukin-8 antibody can be used for the following :

  • For neutralizing the biological activity of recombinant human IL-8 and natural human IL-8.
  • Immunoblotting.
  • ELISA.

生化/生理作用

Interleukin 8 (IL-8) stimulates neutrophils to produce lysosomal enzymes along with myeloperoxidase, α-mannosidase and β-glucuronidase . Goat anti-Interleukin-8 antibody reacts specifically with recombinant and natural human IL-8 but not with recombinant human GROα. Elevated expression of the gene is observed in a number of cancers including chronic spontaneous urticaria and breast cancer, thus serves as a prognostic marker for the same. IL-8 regulates the metastasis and angiogenesis processes during cancer development. IL-8 is responsible for epithelial–mesenchymal transition which plays an important role in providing cancer cells the mobility to invade other neighbouring cells, thereby contributing to metastasis.

外形

Lyophilized from 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD00212220
NACRESNA.41

产品性质

质量水平100
生物来源goat
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式lyophilized powder
species reactivityhuman
technique(s)immunocytochemistry: 5-15 μg/mL
immunohistochemistry: 5-15 μg/mL
neutralization: suitable
western blot: 0.1 μg/mL
储存温度−20℃
Gene Informationhuman ... IL8(3576)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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