产品说明
Amino Acid Sequence
Thr-Gly-Lys-Ala-Ser-Gln-Phe-Phe-Gly-Leu-Met-NH2
一般描述
Hemokinin 1 (HK1) is a a member of the tachykinin peptide family with broad expression, particularly in brain areas.
生化/生理作用
Hemokinin 1 (HK1) is an endogenous agonist for all tachykinin receptors. However, it is highly selective for the NK1 (neurokinin 1) receptor. HK1 and substance-P compete with each other for binding to NK1. HK1 is involved in the B-cell as well as T-cell development.
NK1 tachykinin receptor agonist.
基本信息
经验(实验)分子式 | C54H82N14O14S |
分子量 | 1183.38 |
MDL编号 | MFCD06656083 |
PubChem化学物质编号 | 329815175 |
NACRES | NA.32 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | solid |
颜色 | white |
UniProt登记号 | Q86UU9 |
运输 | wet ice |
储存温度 | −20℃ |
SMILES string | CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H](N)[C@@H](C)O)C(N)=O |
InChI | 1S/C54H84N14O14S/c1-30(2)24-38(51(79)64-35(46(58)74)21-23-83-5)63-44(73)27-59-48(76)39(25-33-14-8-6-9-15-33)66-52(80)40(26-34-16-10-7-11-17-34)67-50(78)37(19-20-42(56)71)65-53(81)41(29-69)68-47(75)31(3)61-49(77)36(18-12-13-22-55)62-43(72)28-60-54(82)45(57)32(4)70/h6-11,14-17,30-32,35-41,45,69-70H,12-13,18-29,55,57H2,1-5H3,(H2,56,71)(H2,58,74)(H,59,76)(H,60,82)(H,61,77)(H,62,72)(H,63,73)(H,64,79)(H,65,81)(H,66,80)(H,67,78)(H,68,75)/t31-,32+,35-,36-,37-,38-,39-,40-,41-,45-/m0/s1 |
InChI key | NYBLUYYRUFKGTB-XJCFQSCISA-N |
Gene Information | human ... TAC4(255061) |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich