产品说明
一般描述
Multidrug resistance associated protein 5 (MRP5) is a short type organic anion pump which belongs to the ATP-binding cassette transporter superfamily.
特异性
Reacts with an internal epitope of MRP5. Does not cross-react with the human MDR1, MRP1, MRP2, MRP3 gene products.
免疫原
human MRP5 (amino acids 722-911) bacterial fusion protein.
生化/生理作用
Multidrug resistance associated protein 5 (MRP5) is involved in pumping out cyclic guanosine monophosphate (cGMP) from the cell. It can also export anti-viral and anti-cancer drugs. MRP5 has been shown to be overexpressed in breast cancer.
外形
Supplied in serum-free culture medium containing 0.7% bovine serum albulin and 0.1% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD03791897 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 200 |
| 生物来源 | rat |
| 偶联物 | unconjugated |
| 抗体形式 | tissue culture supernatant |
| antibody product type | primary antibodies |
| 克隆 | M5II-54, monoclonal |
| 分子量 | antigen 199-200 kDa |
| species reactivity | human |
| 浓度 | 250 μg/mL |
| technique(s) | immunocytochemistry: 1:20-1:50 using acetone-fixed cytospin preparations immunohistochemistry (frozen sections): 1:20 using acetone-fixed sections western blot: 1:20-1:50 |
| 同位素/亚型 | IgG2a |
| UniProt登记号 | O15440 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... ABCC5(10057) |
Sigma-Aldrich
m.cnreagent.com
