产品说明
生化/生理作用
Leucinostatins A and B are the major components of an atypical nonapeptide complex produced by Paecilomyces lilacinus. Leucinostatins display broad bio-activity against gram-positive bacteria, fungi, plants and tumor cell lines. They play a role as uncouplers in the inner mitochondria membrane and inhibit mitochondrial ATP synthesis. Recently, interest in Leucinostatins has focused on other aspects such as understanding their activity: insulin-like growth factor I regulators, ionophore, inhibitors of cell surface expression of viral glycoproteins and their potent in vitro and in vivo anti-trypanosomal activity.
组分
Mixture of Leucinostatin A (Cas# 76600-38-9 / MF: C62H111N11O13) and Leucinostatin B (Cas# 76663-52-0 / MF: C61H109N11O13).
其他说明
Stable at −20 ℃ for at least 2 years.
产品性质
质量水平 | 200 |
生物来源 | (Paecilomyces lilacinus) |
测定 | ≥95% (mixture of Leucinostatin A+B, HPLC) |
形式 | powder |
溶解性 | DMF: 10 mg/mL DMSO: 10 mg/mL ethanol: 10 mg/mL methanol: 10 mg/mL |
储存温度 | −20℃ |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
Sigma-Aldrich