N-Butyldeoxynojirimycin

产品名称：

72599-27-0
N-Butyldeoxynojirimycin
Miglustat
NB-DNJ

产品介绍：

产品说明

一般描述

N-Butyldeoxynojirimycin is an alkylated product of imino sugar deoxynojirimycin.

应用

N-Butyldeoxynojirimycin has been used:

in the inhibition of glycolipid synthesis in neuroblastoma cells
in the inhibition the ceramide-specific glycosyltransferase in hepatocytes
in the inhibition of β-glucosidase (GBA2) using fluorescence- activity assay in human embryonic kidney (HEK293) cells.

包装

1, 5 mg in glass bottle

生化/生理作用

N-Butyldeoxynojirimycin is an inhibitor of glucosyltransferase and α-glucosidases. N-Butyldeoxynojirimycin, also known as misglustat, reduces glycolipid levels by substrate reduction therapy (SRT) and is effectively used for the treatment of glycosphingolipid lysosomal storage disorder, Gaucher disease.
α-glucosidase Inhibitor

基本信息

经验(实验)分子式	C₁₀H₂₁NO₄
分子量	219.28
MDL编号	MFCD00272581
PubChem化学物质编号	24892070
NACRES	NA.32

产品性质

测定	≥98% (TLC)
质量水平	200
形式	film (dried in situ)
溶解性	water: 9.80-10.20 mg/mL, clear, colorless
储存温度	2-8℃
SMILES string	CCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO
InChI	1S/C10H21NO4/c1-2-3-4-11-5-8(13)10(15)9(14)7(11)6-12/h7-10,12-15H,2-6H2,1H3/t7-,8+,9-,10-/m1/s1
InChI key	UQRORFVVSGFNRO-UTINFBMNSA-N
Gene Information	human ... UGCG(7357)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)