产品说明
一般描述
The PDGFRB (platelet derived growth factor receptor β) gene is mapped to human chromosome 5q32. It encodes for a receptor tyrosine kinase.
特异性
This antibody reacts to human CD140b (PDGFR-beta) (Platelet-derived growth factor receptor beta).
免疫原
A peptide corresponding to the C-terminus of human CD140b.
生化/生理作用
PDGFRB (platelet derived growth factor receptor β) acts as a regulator of mesenchymal cells in tumour cells. Upregulation of the gene is observed in gastric cancer, breast and prostate cancers. Mutations in the gene is associated with infantile myofibromatosis.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 质量水平 | 100 |
| 重组 | expressed in HEK 293 cells |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | RM303, monoclonal recombinant monoclonal |
| 形式 | buffered aqueous glycerol solution |
| species reactivity | human |
| technique(s) | immunohistochemistry: 1:500-1:1000 western blot: 1:250-1:500 |
| 同位素/亚型 | IgG |
| NCBI登记号 | 5159 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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