Adenosine 3',5'-cyclic Monophosphorothioate, Rp-Isomer, Triethylammonium Salt-CAS 151837-09-1-Calbiochem

产品说明

一般描述

Note: 5 µmol = 2.23 mg.
A cell-permeable and reversible inhibitor of protein kinase A (K_i = 11 µM). Resistant to hydrolysis by phosphodiesterases. Noncompetitive with respect to ATP.
Cell permeable inhibitor of protein kinase A (K_i = 11 µM). Resistant to hydrolysis by phosphodiesterases. Note: 5 µmol = 2.23 mg

包装

5 μmol in Glass bottle

生化/生理作用

Cell permeable: yes
Product does not compete with ATP.
Target K_i: 11 µM against protein kinase A
Reversible: yes
Primary Target
PKA

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他说明

Kaji, H., et al. 1992. Biochem. Biophys. Res. Commun. 182, 1356.
Van der Kloot, W., and Branisteanu, D.D. 1992. Eur. J. Phys.420, 336.
Yokozaki, H., et al. 1992. Cancer Res.52, 2504.
Butt, E., et al. 1990. FEBS Lett.263, 47.
Dostmann, W.R., et al. 1990. J. Biol. Chem.265, 10484.
Rothermel, J.D. 1988. Biochem. J. 251, 757.
Eckstein, F. 1985. Annu. Rev. Biochem.54, 367.
de Wit, R.J., et al. 1984. Eur. J. Biochem.142, 255.
O′Brian, C.A., et al. 1982. Biochemistry21, 4371.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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