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Hydroxyurea-CAS 127-07-1-Calbiochem

品牌
Sigma-Aldrich
CAS
127-07-1
货号
400046
规格纯度
Anti-neoplastic agent that blocks DNA replication by inhibiting ribonucleotide reductase.
参考价格
1553.42 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
127-07-1
Hydroxyurea-CAS 127-07-1-Calbiochem
Ribonucleotide Reductase Inhibitor I, RNR Inhibitor I
产品介绍:

产品说明

一般描述

Anti-neoplastic agent that blocks DNA replication by inhibiting ribonucleotide reductase. Induces apoptosis in chronic myelogenous leukemia lymphocytes. Reported to enhance the radiation effects in pancreatic adenocarcinoma cells. Releases NO in the presence of oxidizing agents.
Antineoplastic agent. Blocks DNA replication by inhibiting ribonucleotide reductase. Induces apoptosis in chronic myelogenous leukemia lymphocytes.

包装

5 g in Plastic ampoule

生化/生理作用

Primary Target
Inhibiting ribonucleotide reductase
Product does not compete with ATP.
Reversible: no
Cell permeable: no

警告

Toxicity: Carcinogenic / Teratogenic (D)

重悬

Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 2 months at 4°C.

其他说明

Leyden, D., et al. 2000. Anticancer Res.20, 133.
Tsuchiya, K., et al. 1999. Free Radic. Biol. Med. 27, 347.
Anand, S., et al. 1995. Cancer Lett.88, 101.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式CH4N2O2
分子量76.05
MDL编号MFCD00007943
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
颜色 white
溶解性water: 5 mg/mL
运输ambient
储存温度2-8℃
InChI1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)
InChI keyVSNHCAURESNICA-UHFFFAOYSA-N

安全信息

象形图GHS08
警示用语:Danger
危险声明H340 - H361
预防措施声明P201 - P202 - P280 - P308 + P313 - P405 - P501
危险分类Muta. 1B - Repr. 2
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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