产品说明
一般描述
A fluorogenic substrate probe useful for assaying trypsin-like activity of proteasome. Also reported to be a specific substrate for cathepsin B.
A fluorogenic substrate for assaying trypsin-like activity of proteasome. Also serves as a substrate for cathepsin B. Excitation max: 360-380 nm; emission max.: 430-460 nm.
包装
5 mg in Glass bottle
Packaged under inert gas
生化/生理作用
Product does not compete with ATP.
Primary Target
Proteasome
Reversible: no
Cell permeable: no
警告
Toxicity: Standard Handling (A)
序列
Z-Ala-Arg-Arg-AMC
外形
Supplied as hydrochloride salt.
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 3 months at -20°C
其他说明
Geier, E., et al. 1999. Science283, 978.
Dick, T.P., et al. 1998. J. Biol. Chem. 273, 25637.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
经验(实验)分子式 | C33H44N10O7 · 2HCl |
分子量 | 765.69 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | solid |
manufacturer/tradename | Calbiochem® |
储存条件 | OK to freeze protect from light |
颜色 | white to off-white |
溶解性 | DMSO: 200 mg/mL 80% acetic acid: 50 mg/mL methanol: soluble |
荧光 | λex ~380 nm λem ~460 nm |
运输 | ambient |
储存温度 | −20℃ |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich