产品说明
一般描述
The antibody will neutralize the biological activity of recombinant human IL-18 receptor.
免疫原
recombinant human IL-18 receptor extracellular domain, expressed in NS0 cells.
生化/生理作用
IL-18 belongs to the IL-1 cytokine superfamily and is a regulator of innate and acquired immune responses. The immune responses of IL-18 are mediated by its interaction and subsequent signaling by IL-18 receptor complex. The IL-18R complex is made up of α chain that binds to extracellular IL-18 and a β chain that is involved in signal transduction. The IL-18/IL-18R signaling enhances T and NK cell maturation, cytotoxicity and secretion of cytokines.
外形
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.
制备说明
Purified using protein G.
基本信息
| MDL编号 | MFCD02096767 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 200 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | 70625.111, monoclonal |
| 形式 | lyophilized powder |
| species reactivity | human |
| technique(s) | flow cytometry: suitable (2.5μg/SUP>106 cell) immunocytochemistry: 8-25 μg/mL immunohistochemistry: 8-25 μg/mL |
| 同位素/亚型 | IgG1 |
| UniProt登记号 | Q13478 |
| 储存温度 | −20℃ |
| Gene Information | human ... IL18R1(8809) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
