产品说明
应用
ED50 = 1 ng/ml on A20 cells. Does not require any enhancer, as the modified linker sequence already facilitates the formation of active FasL complexes. rhsSuperFasL™ recognizes its receptor Fas (CD95) of the following species: human, rat, mouse.
生化/生理作用
Fas ligand, a protein belonging to the tumor necrosis factor (TNF) family of cytokines, induces apoptosis in cells expressing the cell membrane receptor Fas (CD95/Apo-1).
Fas ligand has also been shown to be involved in the activation of non-apoptotic pathways including proliferation and NF-κ B activation.
法律信息
SuperFas Ligand is a trademark of Alexis Biochemicals Corp.
基本信息
| MDL编号 | MFCD01092558 |
| NACRES | NA.56 |
产品性质
| 质量水平 | 200 |
| 生物来源 | human |
| 重组 | expressed in HEK 293 cells |
| 测定 | ≥95% (SDS-GE) |
| 形式 | lyophilized powder |
| 分子量 | 32 kDa by SDS-PAGE (nonglycosylated form, under reducing conditions) 35 kDa by SDS-PAGE (glycosylated form, under reducing conditions) |
| technique(s) | ligand binding assay: suitable |
| UniProt登记号 | P48023 |
| 储存温度 | −20℃ |
| Gene Information | human ... FASLG(356) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
