N-α-acetyl-Tyr-Val-Ala-Asp-p-nitroanilide

产品名称：

149231-66-3
Ac-YVAD-pNA
N-α-acetyl-Tyr-Val-Ala-Asp-p-nitroanilide
Caspase-1 substrate (Chromogenic)
N-acetyl-L-tyrosyl-L-valyl-L-alanyl-N-(4-nitrophenyl)-L-α-asparagine

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

Ac-YVAD-pNA is a very selective chromogenic substrate for caspase-1, a key mediator of inflammatory processes formerly known as interleukin (IL)-1-converting enzyme. Ac-YVAD-pNA is used to determine caspase-1 activity. Cleavage of Ac-YVAD-pNA by caspase-1 releases pNA (p-nitroanilide), which can be quantified spectrophotometrically at 405 nm.

基本信息

经验(实验)分子式	C₂₉H₃₆N₆O₁₀
分子量	628.63
MDL编号	MFCD00274387
PubChem化学物质编号	329825867
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
储存温度	−20℃
SMILES string	O=C([C@H](CC(O)=O)NC([C@H](C)NC([C@H](C(C)C)NC([C@@H](NC(C)=O)CC1=CC=C(O)C=C1)=O)=O)=O)NC2=CC=C([N+]([O-])=O)C=C2
InChI	1S/C29H36N6O10/c1-15(2)25(34-28(42)22(31-17(4)36)13-18-5-11-21(37)12-6-18)29(43)30-16(3)26(40)33-23(14-24(38)39)27(41)32-19-7-9-20(10-8-19)35(44)45/h5-12,15-16,22-23,25,37H,13-14H2,1-4H3,(H,30,43)(H,31,36)(H,32,41)(H,33,40)(H,34,42)(H,38,39)/t16-,22-,23-,25-/m0/s1
InChI key	YDPNOCSPPGFBPX-XNHCRPTKSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable